LIPITRIN 40 MG / 10 MG 7 TAB

LIPITRIN 40 MG / 10 MG 7 TAB

* LIPITRIN 40/10 (Simvastatin + Ezetimibe) 7 Tablets. Lipid Lowering Drug.
* Indications:
– Primary Hypercholesterolemia:
Lipitrin is indicated as adjunctive therapy to diet for the reduction of elevated total cholesterol (total-C), low-density
lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), & non-high-density lipoprotein cholesterol
(non-HDL-C), & to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary (heterozygous familial &
non-familial) hypercholesterolemia or mixed hyperlipidemia.
– Homozygous Familial Hypercholesterolemia (HoFH): Lipitrin is indicated to reduce elevated total-C levels in patients with HoFH. Patients may also receive adjunctive treatments (e.g. LDL apheresis).
* Dosage & Administration:
– The patient should be placed on a standard cholesterol-lowering diet before receiving Lipitrin & should continue on this diet
treatment with Lipitrin.
– The dosage should be individualized according to the baseline LDL-C level, the recommended goal of therapy, & response.
– Lipitrin should be taken as a single daily dose in the evening, with or without food.
– The recommended usual starting dose is 20/10 mg/day.
– Initiation of therapy with 10/10 mg/day may be considered for patients requiring less aggressive LDL-C reductions.
– Patients who require a larger reduction in LDL-C (greater than 55%) may be started at 40/10 mg/day.
– After initiation of therapy, Lipid levels may be analyzed after 2 or more weeks & dosage adjusted, if needed.
– Dosage in Patients with Homozygous Familial Hypercholesterolemia: The recommended dosage is Lipitrin 40/10 mg/day
or 80/10 mg/day in the evening. Lipitrin should be used as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis)
in these patients or if such treatments are unavailable.
– Use in the elderly: No dosage adjustment is required for elderly patients.
* Store below 30 degrees C.